Mayor West commonly refers to Adam West, a character in the American animated sitcom Family Guy.

Mayor West may also refer to:

• Wild Wild West, Mayor Adam West's cousin and the new mayor of Quahog in season 19 the American animated television series Family Guy voiced by Sam Elliott

• Henry F. West (1796–1856), former mayor of Indianapolis
• Ben West (1911–1974), former mayor of Nashville
• James E. West (politician) (1951–2006), former mayor of Spokane
• Jason West (born 1977), former mayor of the village of New Paltz