Margaret River is a river in Western Australia.

Margaret River may also refer to:

• Margaret River, Northern Territory, a locality

• Margaret River, Western Australia, town
• Margaret River (wine region), a wine region
• Margaret River (Kimberley, Western Australia), a river

• Margaret River Pro, a surfing competition held in Western Australia

• Margaret (disambiguation)
• Margaret Creek, a stream and state waterway in Athens and Meigs Counties, Ohio
• Shire of Augusta-Margaret River