Leontina is female variant of the name Leo or Leon. Notable people with the surname include:
- Leontina Albina Espinoza (b. 1925 - d. 1998), woman from Chile
- Leontina Vaduva (b. 1960), Romanian soprano
- Leontina Vukomanović (b. 1970), female singer from Serbia
See also
- 844 Leontina, an asteroid
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