Henry Mitchell may refer to:

• Henry Mitchell (Irish judge) (c. 1320–1384), Irish judge of the fourteenth century
• Henry Mitchell (New York politician) (1784–1856), American politician
• Henry L. Mitchell (1831–1903), governor of Florida
• Henry Taiporutu Te Mapu-o-te-rangi Mitchell (1877–1944), New Zealand Ngāti Pikiao leader
• John Henry Mitchell, Canadian politician

• Henry Mitchell (footballer) (1874–1943), Australian rules footballer
• Kent Mitchell (Henry Kent Mitchell II, born 1939), American rower and Olympic medalist

• Henry Mitchell (brewer) (1837–1913), of Mitchells & Butlers Brewery
  • His son, Henry Mitchell Junior, known as Harry Mitchell
• Henry Mitchell (engraver) (1835–?), American engraver
• Henry Mitchell (mill owner) (1824–1898), British woollen mill owner
• Henry Mitchell (oceanographer) (1830–1902), American oceanographer, namesake of USC&GS Mitchell
• H. Lane Mitchell (Henry Lane Mitchell, 1895–1978), Public works commissioner in Shreveport, Louisiana, 1934 to 1968

• Henry Mitchell, a fictional character from the television series Charmed; see List of Charmed characters
• Henry Mitchell, a fictional character, Dennis's father in the U.S. comic strip Dennis the Menace
• Henry Ramsay (Neighbours), also known as Henry Mitchell, fictional character in the Australian soap opera Neighbours

• Mitchell Henry (1826–1910), English financier and MP for Galway County
• Harry Mitchell (disambiguation)