Henry Jacobs (1924–2015) was an American humorist.

Henry Jacobs may also refer to:

• Henry Jacobs (priest) (1824–1901), first Dean of Christchurch, NZ
• Henry Eyster Jacobs (1844–1932), American religious figure and writer
• Henry P. Jacobs, American Baptist preacher, schools founder, and state legislator
• Henry Barton Jacobs, American physician and educator
• Henry S. Jacobs (1827–1893), Jamaican-American rabbi

• Harry Jacobs (disambiguation)
• Henry Jacob (1563–1624), English dissenter