A gambit is a type of chess opening move in which one of the pieces is sacrificed in order to achieve a better position.

Gambit may also refer to:

• Gambit (1966 film), a 1966 film starring Michael Caine and Shirley MacLaine
  • Gambit (2012 film), a remake of the 1966 film
• Gambit (unproduced film), an unproduced X-Men franchise film about the eponymous Marvel Comics comicbook superhero

• Gambit (game show), based on the card game blackjack
  • Gambit (British game show), UK version based on the card game blackjack
• Mike Gambit, a character in The New Avengers TV series
• "Gambit", an episode of Blake's 7
• "Gambit" (Star Trek: The Next Generation), a 1993 two-part, seventh-season episode of Star Trek: The Next Generation
• Opening gambit, a short stand-alone action sequence starting many episodes of MacGyver

• The Gambit (record producer) (born 1982), rapper and record producer
• The Gambit (album) by Shelly Manne & His Men

• Gambit (Marvel Comics), a comic book superhero in Marvel Comics
  • Gambit (comic book), a series of comic books featuring the character, first published in 1993
• Gambit (novel), a 1962 Nero Wolfe detective novel by Rex Stout
• Gambit system, a party control system implemented in the Final Fantasy XII and Final Fantasy XII: Revenant Wings video games

• Gambit (forum), a non-profit gambling industry organisation
• Gambit (Scheme implementation), an implementation of the Scheme programming language
• KH-7 Gambit, a reconnaissance satellite used by the United States from July 1963 to June 1967
• KH-8 Gambit 3, a long-lived series of reconnaissance satellites used by the United States from July 1966 to April 1984

• Gambit, a lexical item, or unit
• Gambit Publications, a publisher of chess books
• Gambit (roller coaster), a former roller coaster at Japanese amusement park, Thrill Valley
• Gambit (newspaper), a New Orleans–based newspaper
• Operation Gambit, a part of Operation Neptune
• Contract bridge, opening bid on the 2 level for a long weak suit to be made Trump, thereby hindering opponent bids to reach game in another suit