Diego Velázquez (1599–1660) was a Spanish painter.

Diego Velázquez or Diego Velásquez may also refer to:

• Diego Velázquez de Cuéllar (1465–1524), Spanish conquistador
• Diego Velazquez (born 2001), American actor who played Billy Thunderman in The Thundermans
• Diego Velázquez, actor in Argentine films The Fish Child and The Long Night of Francisco Sanctis
• Diego Velásquez (golfer) (born 1987), Colombian professional golfer

• Velazquez (disambiguation)