DME (3,4-dimethoxy-beta-hydroxyphenethylamine) is a lesser-known psychedelic drug. It is the beta-hydroxy derivative of 3,4-dimethoxyphenethylamine. DME was first synthesized by Alexander Shulgin. In his book PiHKAL, the minimum dosage is listed as 115 mg, and the duration unknown. DME produces few to no effects.^[1] Very little data exists about the pharmacological properties, metabolism, and toxicity of DME.

This substance is a Class A drug in the Drugs controlled by the UK Misuse of Drugs Act.^[2]

• Phenethylamine
• Psychedelics, dissociatives and deliriants