Clorobiocin is an aminocoumarin antibacterial that inhibits the enzyme DNA gyrase.[2][3]

References

  1. ^ [1], http://www.drugbank.ca/drugs/DB03966.
  2. ^ Pojer F, Wemakor E, Kammerer B, Chen H, Walsh CT, Li SM, Heide L (March 2003). "CloQ, a prenyltransferase involved in clorobiocin biosynthesis". Proceedings of the National Academy of Sciences of the United States of America. 100 (5): 2316–21. Bibcode:2003PNAS..100.2316P. doi:10.1073/pnas.0337708100. PMC 151338. PMID 12618544.
  3. ^ Heide L (2009). "Genetic engineering of antibiotic biosynthesis for the generation of new aminocoumarins". Biotechnology Advances. 27 (6): 1006–1014. doi:10.1016/j.biotechadv.2009.05.017. PMID 19463934.


Allikas: https://en.wikipedia.org/wiki/Clorobiocin
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