Azirinomycin is an antibiotic azirine derivative with the molecular formula C4H5NO2 which is produced by the bacterium Streptomyces aureus.[1][2][3] Azirinomycin was first isolated in 1971.[4] Azirinomycin is toxic and therefore it cannot not be used in human medicine.[4]
References
- ^ a b "3-Methyl-2H-azirine-2-carboxylic acid". pubchem.ncbi.nlm.nih.gov.
- ^ Communications, EBCONT. "Azirinomycin". roempp.thieme.de.
- ^ Stapley, Edward O.; Hendlin, David; Jackson, Marion; Miller, A. Kathrine; Hernandez, Sebastian; Mata, Justo M. (25 January 1971). "Azirinomycin. I". The Journal of Antibiotics. 24 (1): 42–47. doi:10.7164/antibiotics.24.42. ISSN 0021-8820.
- ^ a b Diana, Patrizia; Cirrincione, Girolamo (30 January 2015). Biosynthesis of Heterocycles: From Isolation to Gene Cluster. John Wiley & Sons. p. 101. ISBN 978-1-118-96042-4.
Further reading
- Miller, TW; Tristram, EW; Wolf, FJ (January 1971). "Azirinomycin. II. Isolation and chemical characterization as 3-methyl-2(2H) azirinecarboxylic acid". The Journal of Antibiotics. 24 (1): 48–50. doi:10.7164/antibiotics.24.48. PMID 5541332.
- Stapley, EO; Hendlin, D; Jackson, M; Miller, AK; Hernandez, S; Mata, JM (January 1971). "Azirinomycin. I. Microbial production and biological characteristics". The Journal of Antibiotics. 24 (1): 42–7. doi:10.7164/antibiotics.24.42. PMID 5541331.
- Williams, R. M. (22 October 2013). Synthesis of Optically Active Alpha-Amino Acids. Elsevier. p. 126. ISBN 978-1-4832-9295-3.
- Carreira, Erick M. (14 May 2014). Science of Synthesis Knowledge Updates 2011 Vol. 3. Georg Thieme Verlag. p. 137. ISBN 978-3-13-178751-4.
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