At the 2006 US Open, the winner of the girls' doubles competition was the team of Buzărnescu and Olaru, both from Romania, who were seeded second in the tournament. The runners-up were Sharon Fichman and Anastasia Pavlyuchenkova, from Canada and Russia, respectively, who were seeded first. The other semifinalists were the teams of Kramperová and Vaňková, from the Czech Republic, and Klaffner and Paszek, from Austria. Neither of these teams had been seeded.

1. Sharon Fichman / Anastasia Pavlyuchenkova (final)
2. Mihaela Buzărnescu / Ioana Raluca Olaru (champions)
3. Julia Cohen / Corinna Dentoni (second round)
4. Kristina Antoniychuk / Kristína Kučová (second round)
5. Alexandra Dulgheru / Urszula Radwańska (first round)
6. Sorana Cîrstea / Alexandra Panova (third round)
7. Wing Yau Venise Chan / Teliana Pereira (second round)
8. Naomi Cavaday / Dominice Ripoll (second round)

	Semifinals							Final
	1	Fichman Pavlyuchenkova	77	7
		Kramperová Vaňková	63	5				1	Fichman Pavlyuchenkova	5	2
		Klaffner Paszek	1	2				2	Buzărnescu Olaru	7	6
	2	Buzărnescu Olaru	6	6

	First round							Second round							Third round							Quarterfinals
	1	Fichman Pavlyuchenkova	6	6
	WC	Cecil Oudin	3	1				1	Fichman Pavlyuchenkova	6	6
	WC	Anghelescu Augustine	6	3	1				Álvarez Terán Wickmayer	1	0
		Álvarez Terán Wickmayer	2	6	6										1	Fichman Pavlyuchenkova	6	1	6
		Duarte Li	0	0												Gullickson Hampton	3	6	1
		Gullickson Hampton	6	6					Gullickson Hampton	77	6
		Moore Pulido	3	0				8	Cavaday Ripoll	62	1
	8	Cavaday Ripoll	6	6																		1	Fichman Pavlyuchenkova	77	7
	4	Antoniychuk Kučová	6	6																			Kramperová Vaňková	63	5
	WC	Clark Featherston	1	4				4	Antoniychuk Kučová	1	3
		Kramperová Vaňková	6	6					Kramperová Vaňková	6	6
	WC	Embree McHale	3	1												Kramperová Vaňková	7	0	77
		Kalashnikova Killi	7	6											6	Cîrstea Panova	5	6	6
		Boserup C. Jones	5	2					Kalashnikova Killi	3	4
		Brengle Couts	6	3	1			6	Cîrstea Panova	6	6
	6	Cîrstea Panova	1	6	6

	First round							Second round							Third round							Quarterfinals
	5	Dulgheru Radwańska	0	4
		Ito Yamamoto	6	6					Ito Yamamoto	2	5
		Klaffner Paszek	6	6					Klaffner Paszek	6	7
		L. Burdette M. Burdette	4	0												Klaffner Paszek	6	7
		S. Jones Litvak	4	6	77											S. Jones Litvak	4	5
		Nunic Zsilinszka	6	4	61				S. Jones Litvak	7	6
		Lykina Milevskaya	77	3	2			3	Cohen Dentoni	5	2
	3	Cohen Dentoni	65	6	6																		Klaffner Paszek	1	2
	7	Chan Pereira	6	5	6																	2	Buzărnescu Olaru	6	6
		Brodsky Curtis	4	7	3			7	Chan Pereira	2	1
		Berkova Roma	1	2					Frilling Weinhold	6	6
		Frilling Weinhold	6	6												Frilling Weinhold	4	1
		Hofmanova Saidkhodjayeva	6	1	77										2	Buzărnescu Olaru	6	6
		Dy El Allami	4	6	63				Hofmanova Saidkhodjayeva	1	2
		Martić Mrdeža	3	3				2	Buzărnescu Olaru	6	6
	2	Buzărnescu Olaru	6	6

• 2006 US Junior Open – Doubles draws and results at the International Tennis Federation