1,1,2-Trichloroethane, vinyl trichloride or 1,1,2-TCA, is an organochloride solvent with the molecular formula C2H3Cl3 and the structural formula CH2Cl—CHCl2. It is a colourless, sweet-smelling liquid that does not dissolve in water, but is soluble in most organic solvents. It is an isomer of 1,1,1-trichloroethane, and a byproduct of its manufacture.

It is used as a solvent and as an intermediate in the synthesis of 1,1-dichloroethylene.[4]

Toxicity

1,1,2-Trichloroethane may be harmful by inhalation, ingestion, and skin contact. It is a respiratory and eye irritant. 1,1,2-TCA is a central nervous system depressant and inhalation of vapors may cause dizziness, drowsiness, headache, nausea, shortness of breath, and unconsciousness.[5]

The Occupational Safety and Health Administration and National Institute for Occupational Safety and Health have set occupational exposure limits to 1,1,2-Trichloroethane at 10 ppm over an eight-hour time-weighted average.[6]

References

  1. ^ a b c d e f g h NIOSH Pocket Guide to Chemical Hazards. "#0628". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ 1,1,2-Trichloroethane toxicity
  3. ^ "1,1,2-Trichloroethane". Immediately Dangerous to Life or Health Concentrations (IDLH). National Institute for Occupational Safety and Health (NIOSH).
  4. ^ Toxicological profile for 1,1,2-trichloroethane (PDF) (Report). Agency for Toxic Substances and Disease Registry (ATSDR). March 2021. Archived (PDF) from the original on 2022-03-05. Retrieved 2023-08-23.
  5. ^ "Safety (MSDS) data for 1,1,2-trichloroethane" (PDF).
  6. ^ CDC - NIOSH Pocket Guide to Chemical Hazards
Allikas: https://en.wikipedia.org/wiki/1,1,2-Trichloroethane
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