Srem is a region of Serbia and Croatia.

Srem may also refer to:

• Srem District
• FK Srem, a football club
• Sanjak of Srem (Ottoman-era)
• Kingdom of Srem (mediaeval)
• Eparchy of Srem
• Historical Archive of Srem
• Museum of Srem

• Śrem, several places in Poland
• Srem (village), a village in Bulgaria
• Srem Gap, in Antarctica

• Syrmia (disambiguation)