John Cook may refer to:

• John Cook (filmmaker) (1935–2001), Austrian filmmaker
• John Cook (musician) (1918–1984), English organist
• John Kingsley Cook (1911–1994), English artist

• John Pope Cook (1825–1910), American Civil War general
• John Cook (VC) (1843–1879), British soldier and recipient of the Victoria Cross
• John Cook (Medal of Honor, 1847) (1847–1915), American Civil War soldier and Medal of Honor recipient
• John H. Cook (1840–1916), English soldier who fought in the American Civil War

• John Cook (Upper Canada politician) (1791–1877)
• John Henry Cook (1902–1980), provincial politician in Ontario, Canada

• John Arnold Cook, on List of members of the National Congress of Honduras, 2006–10

• John Coke (fl. 1390) or John Cook, in 1390, Member of Parliament (MP) for Truro
• John Cook (fl. 1393), in 1393, MP for Newcastle-under-Lyme
• John Cook (fl.1542), MP for Orford
• John Cook (regicide) (1608–1660), English Solicitor General executed for regicide

• John Cook (governor) (1730–1789), American farmer and governor of Delaware
• John Parsons Cook (1817–1872), U.S. Representative from Iowa
• John C. Cook (1846–1920), U.S. representative and district judge from Iowa
• John Dillard Cook (1792–1852), justice of the Supreme Court of Missouri
• John Cook (Texas politician) (born 1946), mayor of El Paso, Texas
• John R. Cook, member of the Texas House of Representatives

• John Cook (Canadian minister) (1805–1892), Canadian clergyman and educator
• John Cook (professor, born 1739) (1739–1815), Scottish professor and a minister of the Church of Scotland
• John Cook (moderator 1816) (1770–1824), moderator of the General Assembly of the Church of Scotland 1816–1817
• John Cook (moderator 1859) (1807–1869), moderator of the General Assembly of the Church of Scotland 1859
• John Cook (Haddington) (1807–1874), moderator of the General Assembly of the Church of Scotland 1866–1867

• John Howard Cook (1872–1946), British physician, missionary, lecturer
• John Manuel Cook (1910–1994), British archaeologist
• John Call Cook (1918–2012), American geophysicist
• John Cook (Australian author), cognitive scientist and creator of SkepticalScience.com

• John Cook (coach) (born 1956), former women's volleyball head coach
• John Cook (golfer) (born 1957), American professional golfer
• John Cook (Minnesota golfer), American golfer in the 1960s and 1970s, see Minnesota State Open
• John Cook (speedway rider) (born 1958), professional motorcycle speedway rider, world finalist
• John Cook (cricketer) (1946–2007), English cricketer
• John Cook (rugby league) (born 1941), Australian rugby league player

• John Cook (pirate) (died 1684), English buccaneer and pirate
• John Cook (reporter), editor-in-chief of The Intercept
• John Douglas Cook (1808–1868), Scottish journalist, founding editor of the Saturday Review
• John Edwin Cook (died 1859) participated in John Brown's raid on Harpers Ferry
• John F. Cook Sr. (1810–1855), American pastor and educator
• John F. Cook Jr. (1833–1910), American educator and civil rights activist
• John Williston Cook (1844–1922), American educator

• Cook (surname)
• John Coke (disambiguation) (pronounced Cook)
• John Cooke (disambiguation)
• Jonathan Cook (born 1965), British journalist based in Israel