Route nationale 22 (RN22) is a primary highway in Madagascar. The route runs from the capital city of Fenoarivo Atsinanana (Fénérive) to Anjahambe, a city on the eastern coast of the Madagascar.
Selected locations on route (from east to west)
- Fenoarivo Atsinanana (Fénérive) (junction with RN 5)
- Vavatenina - mostly paved, 38 km
- Anjahambe