James Doyle may refer to:

• James Francis Doyle (1840–1913), British architect
• James S. Doyle (born 1935), American journalist
• James William Edmund Doyle (1822–1892), English illustrator and antiquary
• Jimmy Doyle (musician) (1945–2006), Australian guitarist

• James Doyle (mayor) (1938–2016), mayor of Pawtucket, Rhode Island
• James Doyle (New Brunswick politician), member of the New Brunswick Legislative Assembly
• James Doyle II (born 1972), American state legislator in Rhode Island
• James Edward Doyle (1915–1987), United States federal judge in Wisconsin
• James H. Doyle (1897–1982), admiral in the United States Navy
• James H. Doyle Jr. (1925–2018), admiral in the United States Navy
• James William Doyle, Canadian politician
• Jim Doyle (Canadian politician) (born 1943), politician in British Columbia, Canada
• Jim Doyle (James Edward Doyle, born 1945), former governor of Wisconsin

• James Doyle (jockey) (born 1988), English flat racing jockey
• James 'Chick' Doyle (1930–1985), Irish badminton player
• Jamie Doyle (footballer, born 1961), Scottish football player (Partick Thistle, Motherwell, Dumbarton)
• Jamie Doyle (footballer, born 1985), Scottish football player
• Jim Doyle (baseball) (1881–1912), American Major League Baseball infielder
• Jimmy Doyle (1939–2015), Irish retired hurler
• Jimmy Doyle (boxer) (1924–1947), American welterweight boxer

• James Doyle (Ferns), Roman Catholic priest; involved in the Ferns Report, an Irish government inquiry
• James Edwin Doyle (1902–1989), advertising entrepreneur
• James Warren Doyle (1786–1834), Irish bishop