ITS, its or it's may refer to:

• It's, an English contraction of it is or it has
• Its (pronoun), the possessive form of the pronoun it
• Itsekiri language (ISO 639 language code its), a language found in Nigeria and the Niger Delta

• Improvisational Tribal Style, a subgenre of Tribal Style belly dance
• It's (EP), by Teen Top, 2012

• Illinois Traction System, an American railroad
• Industrial Tomography Systems, a manufacturer of process visualization systems based upon the principles of tomography
• International Transportation Service, an American container terminal company

• Indian Theological Seminary, an interdenominational seminary in India
• Sepuluh Nopember Institute of Technology (Institut Teknologi Sepuluh Nopember), a public engineering institute in Surabaya, Indonesia
• Institute for Transport Studies, University of Leeds (ITS Leeds)
• Institute of Technological Studies, Sri Lanka
• Institute of Technology, Sligo, Ireland
• Institute of Transportation Studies, University of California Berkeley, Davis, Irvine and Los Angeles

• Identity, Tradition, Sovereignty, a former political grouping in the European Parliament
• Indian Telecommunication Service, an organised civil service of Government of India
• Indian Trade Service
• International Thespian Society, an honorary organization for high school and middle school theatre students
• International Tracing Service
• International trade secretariat
• International Typographers' Secretariat, a former international trade secretariat
• Irish Texts Society, promoting the study of literature
• Irish Thoracic Society
• Islamic Texts Society, an educational charity based in Cambridge, UK
• Islamic Thinkers Society
• Individualists Tending to the Wild (Individualistas Tendiendo a lo Salvaje), an eco-extremist terrorist group in Mexico

• Incompatible Timesharing System, a computer operating system
• Intelligent tutoring system, an artificial intelligence system used for tutoring
• Internationalization Tag Set, a W3C recommendation for internationalizing XML
• Issue tracking system, computer software that manages product issues

• Inverse transform sampling, a method for generating random numbers from various probability distribution
• Internal transcribed spacer, a section of DNA located within a set of ribosomal genes
• Interrupted time series, a time series of data known to be affected by interventions

• ITS, a ship prefix associated with the Marina Militare, the Italian Navy of the Republic of Italy
• Intelligent transportation system, transportation infrastructure information technology
• Interplanetary Transport System, a project by SpaceX to develop a system capable of transporting humans and cargo to Mars and other destinations in space
• Inter-State Aviation (ICAO airline code ITS), U.S. airline; see List of airline codes (I)

• Integrated Truss Structure, a component of the International Space Station

• International Temperature Scale of 1990 (ITS-90), a temperature calibration standard for measurements in units of kelvin and degrees Celsius
• Network 10, which launched as the Independent Television System
• All pages with titles beginning with ITS
• All pages with titles beginning with ItS
• All pages with titles beginning with Its
• All pages with titles containing its
• IT (disambiguation) for the singular of ITs
• lTS (disambiguation)