Giovanni Targioni-Tozzetti (17 March 1863 – 30 May 1934) was an Italian librettist.

He was best known for his friendship and collaboration with the composer Pietro Mascagni. Most of his libretti were written in collaboration with Guido Menasci.

Targioni-Tozzetti was born and died in Livorno.

• Cavalleria rusticana (1890)
• I Rantzau (1892)
• Regina Diaz (1894)
• Silvano (1895)
• Zanetto (1896)
• Amica (1905)
• La sposa di Nino (1913)
• Pinotta (1932)
• Nerone (1935)

• Works by Giovanni Targioni-Tozzetti at Project Gutenberg
• Works by or about Giovanni Targioni-Tozzetti at the Internet Archive