ERC or Erc may refer to:

• Education and Research Consortium, a US educational organization
• Eleanor Roosevelt College, of the University of California San Diego
• NIOSH Education and Research Centers, of the United States National Institute for Occupational Safety and Health
• Emotion recognition in conversation, a research field to detect emotions from human conversation.

• Component ERA, a baseball statistic
• European Rally Championship
• European Rugby Cup
• FIA European Rallycross Championship

• Erc of Dalriada, king of Dál Riata until 474
• Erc of Slane (died 514), Irish saint
• Erc mac Cairpri, a character from the Ulster Cycle

• ERC (software), an IRC client
• Easily recognizable code, in the North American Numbering Plan
• Electrical rule check
• Electrochemical reduction of carbon dioxide
• Electronics Research Center, a defunct NASA research facility
• Energy release component of a fire
• Epithelial reticular cell
• Epitopoietic Research Corporation - ERC Immunotherapy
• ERMC (cable system), a Eurasian telecommunications system
• Error recovery control
• Ethereum Request for Comments
• European Research Council, a European Union funding body for science
• European Rover Challenge, a robotics competition
• Extrachromosomal rDNA circle
• Panhard ERC, a French armoured fighting vehicle
• Engineering Research Center, a defunct Western Electric subsidiary in Princeton, New Jersey

• ERC (human resources organization), US
• Earnings response coefficient
• Edmund Rice Camps, an Australian children's charity
• Electoral Reform Coalition, in New Zealand
• Ethics Resource Center, US
• European Referendum Campaign, advocating referendums
• European Research Council, European Research Council (ERC)
• European Resuscitation Council, for resuscitation medicine
• Republican Left of Catalonia (Catalan: Esquerra Republicana de Catalunya), a political party in Spain
• Employee Relocation Council or Worldwide ERC
• East Renfrewshire Council, Scotland
• Employee Retention Credit, a U.S. tax credit