Centennial Bridge may refer to:

• Centennial Bridge (New Brunswick), over the Miramichi River, in Northumberland County, New Brunswick, Canada

• Haikou Century Bridge

• Centennial Bridge, Panama, which crosses the Panama Canal

• Centennial Bridge (Leavenworth, Kansas), over the Missouri River, connecting Leavenworth, Kansas and Platte County, Missouri
• Centennial Bridge (Center Valley, Pennsylvania), an arch bridge in Center Valley, Pennsylvania
• Centennial Covered Bridge, a replica wooden covered bridge in Cottage Grove, Oregon
• Rock Island Centennial Bridge, connecting Rock Island, Illinois and Davenport, Iowa
• Teegarden-Centennial Covered Bridge, over Little Beaver Creek, in Columbiana County, Ohio
• Veterans Memorial Centennial Bridge, in Idaho (formerly Bennett Bay Centennial Bridge)

• The codename for the application bridge used to port Win32 desktop apps to the Universal Windows Platform