Andy Roddick did not defend his title as he had retired from professional tennis in September 2012.

John Isner won the title after two previous final appearances, defeating Kevin Anderson in the final, 6–7^(3–7), 7–6^(7–2), 7–6^(7–2).

The top four seeds receive a bye into the second round.

	Semifinals							Final
	1	John Isner	6	4	77
	7	Lleyton Hewitt	4	6	65
								1	John Isner	63	77	77
								2	Kevin Anderson	77	62	62
		Ryan Harrison	3	63
	2	Kevin Anderson	6	77

	First round							Second round							Quarterfinals							Semifinals
								1	J Isner	711	4	7
		A Falla	1	79	2			WC	C Harrison	69	6	5
	WC	C Harrison	6	67	6										1	J Isner	77	77
		J Blake	77	4	77											J Blake	61	65
	Q	T Smyczek	63	6	64				J Blake	6	6
		R Ram	3	4				8	E Donskoy	3	2
	8	E Donskoy	6	6																		1	J Isner	6	4	77
																						7	L Hewitt	4	6	65
								3	I Dodig	6	63	6
		R Berankis	77	2	710				R Berankis	1	77	3
	Q	M Zverev	64	6	68										3	I Dodig	6	3	0
	WC	D Kudla	5	4											7	L Hewitt	1	6	6
	WC	R Williams	7	6				WC	R Williams	66	4
		É Roger-Vasselin	4	4				7	L Hewitt	78	6
	7	L Hewitt	6	6

	First round							Second round							Quarterfinals							Semifinals
	6	M Fish	6	2	5
		M Russell	4	6	7				M Russell	7	3	0r
		J Sock	5	4					S Giraldo	5	6	3
		S Giraldo	7	6												S Giraldo	3	6	62
		R Harrison	6	2	6											R Harrison	6	3	77
		M Matosevic	2	6	3				R Harrison	6	6
								4	I Sijsling	4	3
																							R Harrison	3	63
	5	Y-h Lu	6	7																		2	K Anderson	6	77
	Q	K King	3	5				5	Y-h Lu	5	2
		D Istomin	6	6					D Istomin	7	6
		L Lacko	1	3												D Istomin	3	6	3
	Q	M Ebden	6	0											2	K Anderson	6	3	6
	SE	I Karlović	2	0r				Q	M Ebden	79	2	2
								2	K Anderson	67	6	6

	First round							Second round							Qualifying competition
	1	Matthew Ebden	6	6
		Santiago González	4	1
								1	Matthew Ebden	6	6
									Dean O'Brien	1	1
		Dean O'Brien	77	63	6
		Juan Carlos Spir	65	77	2
															1	Matthew Ebden	6	77
																Chris Guccione	4	62
		Mark Verryth	5	2
		Chris Guccione	7	6
									Chris Guccione	6	6
								6	Yūichi Sugita	4	2
		André Sá	6	2r
	6	Yūichi Sugita	2	1

	First round							Second round							Qualifying competition
	2	Tim Smyczek	6	6
		Luke Saville	1	3
								2	Tim Smyczek	6	6
									Mitchell Frank	1	4
		Mitchell Frank	3	6	6
	WC	Nathan Pasha	6	2	4
															2	Tim Smyczek	7	77
															7	Donald Young	5	63
		Marcelo Demoliner	3	5
		Saketh Myneni	6	7
									Saketh Myneni	63	3
								7	Donald Young	77	6
		Cătălin-Ionuț Gârd	2	2
	7	Donald Young	6	6

	First round							Second round							Qualifying competition
	3	Somdev Devvarman	6	6
		Patrick Davidson	0	2
								3	Somdev Devvarman	3	4
									Prakash Amritraj	6	6
		Jason Jung	2	0
		Prakash Amritraj	6	6
																Prakash Amritraj	4	2
															5	Mischa Zverev	6	6
		Takura Happy	6	6
	WC	Eric Sock	1	2
									Takura Happy	3	3
								5	Mischa Zverev	6	6
	WC	Nathan Rakitt	4	3
	5	Mischa Zverev	6	6

	First round							Second round							Qualifying competition
	4	Jimmy Wang	64	0r
		Kevin King	77	1
									Kevin King	64	77	6
									Tyler Hochwalt	77	64	1
		Tyler Hochwalt	6	6
		Jean-Yves Aubone	3	4
																Kevin King	2	6	6
															8	Robby Ginepri	6	4	4
		Jeff Dadamo	6	6
	WC	Christopher Eubanks	2	3
									Jeff Dadamo	6	1	3
								8	Robby Ginepri	3	6	6
		Andrew Carter	3	1
	8	Robby Ginepri	6	6

• Main Draw
• Qualifying Draw