West Virginia Route 20 is a major north–south state highway in the U.S. state of West Virginia. The southern terminus of the route is at U.S. Route 52 in Bluewell, a small unincorporated suburb of Bluefield. The northern terminus is at West Virginia Route 7 three miles (5 km) east of New Martinsville. WV Route 20 is the longest state route in West Virginia.

• Concord University, Athens
• Pipestem Resort State Park, Pipestem
• Bluestone State Park, Summers County
• Bluestone Lake, Summers County
• Sandstone Falls, New River Gorge National Park and Preserve, north of Hinton
• Holly River State Park, Webster County

County	Location	mi	km	Destinations	Notes
Mercer	Bluewell	0.00	0.00	US 52 – Bluefield, Welch, Bramwell Historic District
	Littlesburg			WV 108 – Bluefield	Construction starts mid to late summer of 2024
	Princeton			WV 104 east
				US 19	traffic circle around Mercer County Courthouse
				WV 104 to I-77 / US 460
Summers	​			WV 3 east – Alderson	south end of WV 3 overlap
	​			WV 3 west – Beckley	north end of WV 3 overlap
	Hinton			WV 107 south (2nd Avenue)
	​			CR 7 (Meadow Creek Road) to I-64 – Beckley, Lewisburg
Greenbrier	Rainelle			US 60 west – Charleston	south end of US 60 overlap
	Charmco			US 60 east – Lewisburg	north end of US 60 overlap
Nicholas	Nettie			WV 39 west – Summersville	south end of WV 39 overlap
	Fenwick			WV 39 east / WV 55 east – Richwood	north end of WV 39 overlap; south end of WV 55 overlap
	Craigsville			WV 55 west – Muddlety, Summersville	north end of WV 55 overlap
Webster	​			WV 82 west to US 19 / I-79 – Birch River
	Webster Springs			WV 15 east – Valley Head	south end of WV 15 overlap
	​			WV 15 west – Flatwoods	north end of WV 15 overlap
Upshur	Rock Cave			WV 4 south – Sutton
	Buckhannon			CR 12 / CR 151 (Main Street)	former US 33 / US 119 south
				US 33 to US 119 south / I-79 – Weston, Elkins	interchange (future US 48); south end of US 119 overlap
	​			US 119 north – Philippi	north end of US 119 overlap
Harrison	​			WV 57 east – Philippi
	​			I-79 – Charleston, Clarksburg	I-79 exit 115
	Nutter Fort			WV 58 east – Stonewood, Bridgeport
				WV 98 west to US 19
	Clarksburg			US 50 to I-79 – Parkersburg, Bridgeport	interchange
				US 19 south (Milford Street)	south end of US 19 overlap
				US 50 – Parkersburg, Bridgeport	interchange
	Shinnston			US 19 north – Shinnston	north end of US 19 overlap
Wetzel	​	256.15	412.23	WV 7 – New Martinsville, Morgantown
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus