Step Brothers may refer to:
- The Four Step Brothers, an African-American dance group
- Step-brother, a member of a stepfamily in which someone has a sibling with remarried parents.
- Step Brothers (duo), an American hip hop supergroup and record production team
- Step Brothers (film), a 2008 American comedy film
- Stepbrothers (1957 film), a 1957 Japanese drama film
- Step Brothers (EP), by G-Eazy and Carnage (2017)
See also
- Step-brother, male children born of two different families who have been joined by the marriage of at least one of their respective parents