Smithies is a surname. It may refer to:

• Alex Smithies (born 1990), English football player
• Bob Smithies (1934–2006), journalist and crossword compiler
• Catherine Smithies (1785–1877), English philanthropist and campaigner
• Frank Smithies (1912–2012), British mathematician
• John Smithies (1802–1872), Wesleyan missionary
• John J. Smithies (born 1954), founding director of the Australian Centre for the Moving Image
• Karen Smithies (born 1969), English international cricketer
• Oliver Smithies (1925–2017), British biologist
• Thomas Bywater Smithies (1817–1883), English radical publisher and campaigner

• All pages with titles containing Smithies