Orkhon (Mongolian: Орхон) may refer to:
- Orkhon River, Mongolia
- Orkhon Valley, the landscape around that river
- Orkhon Province, an Aimag (province) in Mongolia
- several Sums (districts) in different Mongolian Aimags:
- Orkhon script, a historic script of Turkic origin
- Orkhon inscriptions, inscriptions of Bilge Kagan, Kül Tiğin, and Tonyukuk in Unicode
- Orhun (name), list of people named the Turkish version of Orkhon
- Orkhoe, the Greek word for Uruk, a prominent Sumerian city-state