John Francis may refer to:
- John Francis (priest) (died 1724), Irish Anglican priest
- John Francis (sculptor) (1780–1861), English sculptor
- John Brown Francis (1791–1864), United States Senator from Rhode Island
- John F. Francis (1808–1886), American painter
- John Francis (publisher) (1811–1882), English businessman and campaigner against "taxes on knowledge"
- John Deffett Francis (1815–1901), Welsh portrait painter and art collector
- John M. Francis (1823–1897), American journalist and diplomat
- John Michael Francis, historian
- John Francis (bushranger) (c. 1825–?), Australian bushranger
- J. J. Francis (John Joseph Francis, 1839–1901), counsel in the British Colony of Hong Kong
- John Francis (New Zealand cricketer) (1846–1891), New Zealand cricketer
- John R. Francis (1856–1913), American physician and educator
- John J. Francis (musician) (1945-2022), Australian musician
- John J. Francis (New Jersey judge) (1903–1984), American politician and State Supreme Court Justice
- Jack Francis (John Charles Francis, 1908–2001), Australian cricketer and Australian rules football player
- John G. F. Francis (born 1934), English computer scientist
- John Francis (environmentalist) (born 1946), American environmentalist
- John Francis (footballer) (born 1963), English association football player
- John Francis (boxer) (born 1965), Indian Olympic boxer
- John Francis (English cricketer) (born 1980), English cricketer
See also
- Jon Francis (born 1964), former American football player
- John Francis Regis (1597–1640), saint of the Roman Catholic Church
- All pages with titles containing John Francis