Guthrie may refer to:

• Guthrie (surname), a family name originating in Scotland
• Guthrie baronets in the United Kingdom
• Clan Guthrie, a Scottish clan
• Guthrie Govan (born 1971), British guitar virtuoso and guitar teacher

• Hundred of Guthrie, County of Way, South Australia
• Guthrie, Ontario, Canada
• Guthrie, Angus, Scotland

• Guthrie, Arizona
• Guthrie, Illinois
• Guthrie, Indiana
• Guthrie, Kentucky
• Guthrie, Michigan
• Guthrie, Missouri
• Guthrie, Oklahoma
• Guthrie, Texas
• Guthrie, West Virginia
• Guthrie, Wisconsin
• Guthrie County, Iowa
• Guthrie Township, Hubbard County, Minnesota

• Guthrie (company), a Malaysian plantation company
• Guthrie test, a medical test performed on newborn infants to detect phenylketonuria
• Guthrie Theater, theater company in Minneapolis, Minnesota
• Guthrie's, an American restaurant chain

• All pages with titles containing Guthrie