Edward Burke may refer to:

• Edward A. Burke (1839–1928), Louisiana state treasurer
• Edward T. Burke (1870–1935), North Dakota Supreme Court justice
• Edward J. Burke (1876–1935), Wisconsin legislator
• Edward R. Burke (1880–1968), American politician
• Edward H. Burke (1886–1955), American politician and lawyer
• Edward M. Burke (born 1943), Chicago, Illinois alderman
• Edward L. Burke (1899–1982), public official in Vermont

• Eddie Burke (baseball) (1866–1907), American baseball player
• Edward Burke (American football) (1907–1967), selected to the 1928 College Football All-America Team
• Edward Burke (cricketer) (born 1870), Jamaican cricketer
• Ed Burke (hammer thrower) (born 1940), hammer thrower, American flagbearer at 1984 Olympic games
• Edward Burke (basketball) (1945–2009), American basketball coach
• Ted Burke (1877–1967), Australian rules footballer
• Ed Burke (high jumper), winner of the high jump at the 1937 USA Indoor Track and Field Championships

• Edward Burke (priest) (1847–1915), priest, president of Carlow College, and founder of St. Joseph's Academy
• Ed Burke (musician) (1909–1988), American musician

• Edmund Burke (disambiguation)
• Edward C. Burks (1821–1897), American jurist