Deutsch is a surname, meaning German in German. When transliterated to other languages, it may also be spelled as Deutch, Deitch, Deich, Teutsch.

• Adam Deutsch (born 1995), Swedish ice hockey player
• Adolph Deutsch, Academy Award-winning composer
• Alex Deutsch, founder of Deutsch Group
• Alexander Deutsch, German planetologist (active since 1984)
• Alexander Nikolaevich Deutsch, Russian astronomer (active 1926–1985)
• Alina Deutsch, Romanian-American electronics engineer
• Alvin Deutsch,
• Ana Deutsch (born 1940), psychologist and co-founder of the Program for Torture Victims
• André Deutsch, publisher in London
• Andrew Deutsch (born 1968), sound artist
• Armand Deutsch,
• Armelle Deutsch,
• Armin Joseph Deutsch (1918–1969), American astronomer and science fiction author
• Arnold Deutsch, NKVD operative who recruited Kim Philby
• Avraham Deutsch,
• Babette Deutsch (1895–1982), American author
• Barbu Nemțeanu (1887–1919), born Benjamin Deutsch, Romanian poet
• Beatie Deutsch (nee Rabin; born 1989), Haredi Jewish American-Israeli marathon runner
• Bence Deutsch,
• Boris Deutsch,
• Caroline Deutsch (1846–after 1903), German novelist
• Celia Deutsch,
• Chaim Deutsch, American politician
• Charles Deutsch, French engineer
• Charlie Deutsch,
• David Deutsch (born 1953), physicist
• David Deutsch (ad executive) (c. 1929 – 2013), American advertising executive
• Donny Deutsch,
• Diana Deutsch, British-born, American perceptual and cognitive psychologist
• Eliot Deutsch,
• Erik Deutsch,
• Ernst Deutsch (1890–1969), German actor
• Filip Deutsch (1828–1919), Croatian nobleman and industrialist
• Francine Deutsch,
• Fred Deutsch,
• George Deutsch, ex-NASA press officer
• Gerhard Deutsch,
• Gerti Deutsch,
• Gotthard Deutsch (1859–1921), scholar of Jewish history
• Gustav Deutsch,
• Hans Deutsch,
• Harold C. Deutsch (1904–1995), American historian and writer
• Harri Deutsch, (−2000), German publisher
• Helen Deutsch,
• Helene Deutsch, Austrian-born American psychologist
• Helmut Deutsch (born 1945), Austrian classical pianist
• Herbert Deutsch (1932–2022), American composer
• Hubert Deutsch,
• Immanuel Oscar Menahem Deutsch (1829–1873), German oriental scholar
• Jan Deutsch,
• Joel Deutsch,
• John James Deutsch, Canadian economist
• Josef Deutsch,
• Josh Deutsch,
• Julio Deutsch (1859–1922), Croatian architect
• Julius Deutsch (1884–1968), Austrian politician
• Karl Deutsch (1912–1992), Czech social and political scientist
• Kevin Deutsch,
• Kurt Deutsch,
• Ladislas Deutsch, pen name of László Detre (1874–1939), Hungarian microbiologist
• Lea Deutsch (1927–1943), Croatian Jewish child actress who was murdered during the Holocaust
• Leo Deutsch (1855–1941) (known as Lev Deich in Russia), Russian revolutionary
• Linda Deutsch,
• Lindsay Deutsch,
• Lorànt Deutsch,
• Louis "Red" Deutsch (1890–1983), American boxer and owner of the "Tube Bar" in Jersey City
• L. Peter Deutsch, programmer and creator of the Ghostscript software
• Maria Deutsch,
• Mark Deutsch (musician), musician, inventor of bazantar
• Mark Deutsch (journalist) (Russian: Марк Дейч, also Deutch, Deich, Deitch, 1945–2012), Russian journalist
• Martin Deutsch, physicist, discoverer of positronium
• Martin Deutsch (psychologist) (1926–2002), American developmental psychologist
• Maury Deutsch,
• Max Deutsch, French-Austrian composer and director
• Mel Deutsch,
• Morton Deutsch (1920–2017), social psychologist and researcher in conflict resolution
• Naomi Deutsch,
• Nathaniel Deutsch,
• Niklaus Manuel Deutsch I (c. 1484–1530), Swiss artist
• Oscar Deutsch (1893–1941), founder of the British Odeon cinema chain
• Oskar Deutsch (born 1963), Austrian entrepreneur and President of the Jewish Community of Vienna
• Otto Erich Deutsch (1883–1967), Austrian musicologist and creator of the Deutsch catalogue of Schubert's compositions
• Patti Deutsch (1943–2017), 1970s game-show celebrity
• Peter Deutsch (born 1957), American politician
• Péter Deutsch (born 1968), Hungarian athlete
• Richard Deutsch,
• Robert Deutsch,
• Samuel Deutsch,
• Sándor Hatvany-Deutsch (1852–1913), Hungarian industrialist and art patron
• Sarah Deutsch,
• Seymon Deutsch (1935–2013), American bridge player
• Simion Deutsch,
• Simon Deutsch (1808–1877), Austrian Jewish writer and revolutionary
• Stephen Deutsch,
• Tamás Deutsch,
• Tamás Deutsch (politician),
• Verlag Harri Deutsch,
• Walter Deutsch (1923–2025), Austrian musicologist
• Yaron Deutsch,

• Fran Deitsch (1927–2011, married name Fran Landesman), American lyricist and poet
• Gene Deitch
• Kim Deitch
• Howard Deutch, film director
• John M. Deutch
• Madelyn Deutch, writer, director, actress and musician
• Zoey Deutch, actress and producer
• Georg Daniel Teutsch
• János Mattis-Teutsch