Crick is a surname. Notable people with the surname include:

• Bernard Crick (1929–2008), British political scientist
• Francis Crick (1916–2004), British scientist and joint discoverer of the structure of DNA
• George Crick (1888–1982), English footballer
• Jamie Crick (1966–2023), English radio broadcaster
• Kyle Crick (born 1992), American baseball pitcher
• Mark Crick, British author and photographer
• Michael Crick (born 1958), British journalist and biographer
• Nancy Crick (1932–2002), Australian figure from the euthanasia debate
• Odile Crick (1920–2007), wife of Francis Crick
• Walter Drawbridge Crick (1857– 1903), English businessman, amateur geologist and palaeontologist

Fictional characters:

• Harold Crick, protagonist of a 2006 film Stranger than Fiction

• Krick