Abd al-Samad ibn Ali al-Hashimi (Arabic: عبد الصمد بن علي الهاشمي) was an eighth century Abbasid personage. He served as the governor of al-Jazira for the Abbasid Caliphate.

Abd al-Samad was the son of Ali ibn Abd Allah ibn al-Abbas. He was a paternal uncle of the first two Abbasid caliphs al-Saffah (r. 750–754) and al-Mansur (r. 754–775), making him one of the "uncles" ('umumah) that held a high degree of influence during the early years following the Abbasid Revolution.

His nephew, al-Mansur appointed him^[1][2] governor of Medina and Mecca in 772. He was dismissed from the office in 776.

In 775, Al-Fadl ibn Salih was appointed governor of the region of al-Jazira north of Damascus by the Abbasid caliph al-Mahdi. He moved to al-Jazira the same year. Al-Fadl returned to Damascus following his trip to Jerusalem in 780 where he accompanied al-Mahdi as part of his entourage.^[3] It was around this time when he was deposed as governor of al-Jazira and replaced by Abd al-Samad ibn Ali.^[4]

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