The A64 autoroute is a motorway in southwestern France. It is also called the La Pyrénéenne and numbered the European route E80. It is a toll road for part of its length.

Aligned East-West, it connects Toulouse to Bayonne via Tarbes and Pau. Its length is approximately 287 km with 2x2 lanes and 2x3 lanes towards Toulouse. It is operated by ASF.

• 01 km 11 Start of autoroute in junction with: RD1 to junction 5.1 of the A63 autoroute to Biarritz.
• 02 km 11 (Briscous) Towns served: Briscous
• 04 km 16 (Urt) Towns served: La Bastide-Clairence
• 05 km 23 (Guiche) Towns served: Guiche
  • Péage de Sames
  • Service Area: Hastingues
• Exchange A64-A641 Junction with A641 spur to Peyrehorade.
• 07 km (Salies-de-Béarn) Towns served: Salies-de-Béarn
  • Rest Area: Magret
  • Rest Area: Haut de Départ
• 08 km (Orthez) Towns served: Orthez
  • Service Area: Lacq-Audejos
• 09 (Artix) Towns served: Mourenx
• 10 (Pau) Towns served: Pau
  • Rest Area: Serres-Morlaàs
• 11 (Soumoulou) towns served: Soumoulou, Nousty, Lourdes via RD940.
  • Service Area: Les Pyrénées
• 12 (Tarbes-ouest) Towns served: Tarbes, Lourdes via RN21
• 13 km 145 (Tarbes-est) Towns served: Tarbes
  • Rest area km 156 Bordes
• 14 (Tournay) Towns served: Tournay, Bagnères-de-Bigorre
• 15 km 171 (Capvern) Towns served: Capvern-les-Bains
  • Rest Area km 172: Les Bandouliers/Le Lac St-Martin
• 16 km 175 (Lannemezan) Towns served: Lannemezan
  • Rest area km 182: Le Pic du Midi
• Exchange A64-A645 km 192 Junction with A645 spur to Montréjeau, Bagnères-de-Luchon, Aran Valley (Spain)
  • Service Area: Comminges
• 18 km 207 (Saint Gaudens) Towns served: Saint-Gaudens
  • Péage de Lestelle
• 19 km 218 (Lestelle de St-Martory) Towns served: Lestelle-de-Saint-Martory
• 20 km 222 (Saint-Martory) Towns served: Saint-Girons, Saint-Martory
• 21 (Boussens) Towns served: Boussens, Martres-Tolosane
• 22 km 233 (Martres-Tolosane) Towns served: Martres-Tolosane
  • Rest Area km 237: Vergers/Bleue
• 23 km 240 (Cazères) Towns served: Cazères, Le Fousseret
• 24 km 244 (Lavelanet de Comminges) Towns served: Lavelanet-de-Comminges
• 25 (Saint Elix le Chateau) Towns served: Saint-Élix-le-Château
• 26 (Laffite Vigordane) Towns served: Lafitte-Vigordane, Carbonne
• 27 km 254.5 (Carbonne) Towns served: Carbonne
  • Service Area: km 257 Garonne/Volvestre
• 28 km 258 (Capens) Towns served: Capens
• 29 km 260 (Noé) Towns served: Noé
• 30 km 261.5 (Longages) Towns served: Lavernose-Lacasse
• 31 (Mauzac) Towns served: Mauzac
• 32 km 265 (Le Fauga) Towns served: Le Fauga
• 33 km 269 (Muret-Sud) Towns served: Muret
• 33 km 269 (Muret-Centre) Towns served: Muret, Rieumes via RD3
• 35 km 274 (Muret-nord) Towns served: Muret, Toulouse via RN117
  • Péage de Muret
• 36 km 281 (Roques) Towns served: RN264 and RN20 to Pamiers
• 37 km 283 (Francazal) Towns served: Toulouse
• 38 km 286 (Le Chapitre) Towns served: Toulouse
• Exchange A64-A620 Autoroute joins the A620 the Périphérique of Toulouse

• A64 Motorway on Saratlas