The 2000 WNBA All-Star Game was played on July 17, 2000, at America West Arena in Phoenix, Arizona. This was the 2nd annual WNBA All-Star Game.

The West defeated the East, 73–61, and Tina Thompson was named the All-Star Game MVP after recording 13 points and 11 rebounds.^[1]

Eastern Conference All-Stars Pos. Player Team Selection # Starters G Teresa Weatherspoon New York Liberty 2nd G Nikki McCray Washington Mystics 2nd F Chamique Holdsclaw Washington Mystics 2nd F Sue Wicks New York Liberty 1st F Taj McWilliams Orlando Miracle 2nd Reserves G Shannon Johnson Orlando Miracle 2nd G Merlakia Jones Cleveland Rockers 2nd G Nykesha Sales Orlando Miracle 2nd G Andrea Stinson Charlotte Sting 1st F Wendy Palmer Detroit Shock 1st C Tari Phillips New York Liberty 1st

Western Conference All-Stars Pos. Player Team Selection # Starters G Ticha Penicheiro Sacramento Monarchs 2nd G Cynthia Cooper 1 Houston Comets 2nd F Sheryl Swoopes Houston Comets 2nd F Tina Thompson Houston Comets 2nd C Lisa Leslie Los Angeles Sparks 2nd Reserves G Betty Lennox Minnesota Lynx 1st G Mwadi Mabika Los Angeles Sparks 1st F Delisha Milton Los Angeles Sparks 1st F Brandy Reed Phoenix Mercury 1st F Katie Smith 2 Minnesota Lynx 1st F Natalie Williams Utah Starzz 2nd C Yolanda Griffith Sacramento Monarchs 2nd

• ¹ Injured
• ² Starting in place of injured player

The coach for the Western Conference was Houston Comets coach Van Chancellor. The coach for the Eastern Conference was New York Liberty coach Richie Adubato.