The 1980 Campionati Internazionali di Sicilia, also known as the Palermo Grand Prix or the Sicilian Open, was a men's tennis tournament played on outdoor clay courts in Palermo, Italy that was part of the 1980 Volvo Grand Prix. It was the second edition of the tournament and took place from 8 September until 14 September 1980. First-seeded Guillermo Vilas won the singles title.
Finals
Singles
Guillermo Vilas defeated 
Paul McNamee 6–4, 6–0, 6–0
- It was Vilas' 3rd singles title of the year and the 49th of his career.
Doubles
Ricardo Ycaza / 
Gianni Ocleppo defeated 
Víctor Pecci / 
Balázs Taróczy 6–2, 6–2
References
- ^ "1980 Palermo – Singles draw". Association of Tennis Professionals (ATP).
- ^ "1980 Palermo – Doubles draw". Association of Tennis Professionals (ATP).