Two-time defending champion Novak Djokovic defeated Matteo Berrettini in the final, 6–7^(4–7), 6–4, 6–4, 6–3 to win the gentlemen's singles tennis title at the 2021 Wimbledon Championships.^[1] It was his sixth Wimbledon title and 20th major men's singles title overall, tying Roger Federer and Rafael Nadal's all-time record total.^[2]

Djokovic was the first man to win the Australian Open, French Open and Wimbledon titles in the same calendar year since Rod Laver in 1969, and the first to achieve the Surface Slam (winning majors on three different surfaces in a calendar year) since Nadal in 2010. He became the fifth man in the Open Era to win the Channel Slam (French Open—Wimbledon double).^[3][4][5]

Djokovic and Daniil Medvedev were in contention for the world No. 1 singles ranking; Djokovic retained the top ranking when Medvedev lost in the fourth round.

This event marked the final professional singles appearance of 20-time major champion, eight-time Wimbledon champion and former world No. 1 Roger Federer; he lost in the quarterfinals to Hubert Hurkacz. Federer was the oldest man in the Open Era to reach the Wimbledon quarterfinals, and the oldest man to reach a major quarterfinal since Ken Rosewall in December 1977.^[6] His fourth-round victory marked 105 match wins at Wimbledon. The 18 quarterfinals and 119 matches he has contested at Wimbledon are both tournament records.^[7][8]

Berrettini was the first Italian man to reach a major final since Adriano Panatta at the 1976 French Open and the first to do so at Wimbledon.^[9] Zhang Zhizhen was the first Chinese man to qualify for the Wimbledon main draw in the Open Era.^[10][11] Márton Fucsovics was the first Hungarian to reach a men's singles major quarterfinal since Balázs Taróczy at the 1981 French Open, and the first to do so at Wimbledon since József Asbóth in 1948.^[12]

It was the first time since 2017 that two-time champion Andy Murray participated.^[13] For the first time since 2002, the grass court seeding formula was abandoned and the standard ranking system based on the ATP rankings was permanently adopted, like at the other three majors.^[14][15]

Click on the seed number of a player to go to their draw section.

	Quarterfinals									Semifinals									Final
	1	Novak Djokovic	6	6	6
		Márton Fucsovics	3	4	4
										1	Novak Djokovic	77	7	7
										10	Denis Shapovalov	63	5	5
	25	Karen Khachanov	4	6	7	1	4
	10	Denis Shapovalov	6	3	5	6	6
																			1	Novak Djokovic	64	6	6	6
																			7	Matteo Berrettini	77	4	4	3
	7	Matteo Berrettini	6	5	7	6
	16	Félix Auger-Aliassime	3	7	5	3
										7	Matteo Berrettini	6	6	63	6
										14	Hubert Hurkacz	3	0	77	4
	6	Roger Federer	3	64	0
	14	Hubert Hurkacz	6	77	6

	First round									Second round									Third round									Fourth round
	1	N Djokovic	4	6	6	6
	WC	J Draper	6	1	2	2				1	N Djokovic	6	6	6
	Q	T Barrios Vera	77	4	4	64					K Anderson	3	3	3
		K Anderson	64	6	6	77													1	N Djokovic	6	6	79
		A Seppi	4	6	7	6													Q	D Kudla	4	3	67
		J Sousa	6	4	5	2					A Seppi	2	4	2
	Q	D Kudla	5	4	77	6	6			Q	D Kudla	6	6	6
	30	A Davidovich Fokina	7	6	64	3	3																					1	N Djokovic	6	6	6
	17	C Garín	66	6	3	6	6																					17	C Garín	2	4	2
	Q	B Zapata Miralles	78	3	6	3	2			17	C Garín	77	6	2	77
	Q	M Polmans	6	7	4	6				Q	M Polmans	63	2	6	65
	PR	Y-h Lu	2	5	6	1													17	C Garín	6	6	4	6
		P Martínez	6	2	6	6														P Martínez	4	3	6	4
		S Travaglia	3	6	4	4					P Martínez	6	6	4	77
	Q	C O'Connell	6	2	65	6	4			13	G Monfils	3	4	6	65
	13	G Monfils	4	6	77	4	6

	First round									Second round									Third round									Fourth round
	9	D Schwartzman	6	6	6
		B Paire	3	4	0					9	D Schwartzman	4	6	6	6
		M Cecchinato	3	4	0					WC	L Broady	6	2	1	4
	WC	L Broady	6	6	6														9	D Schwartzman	3	3	78	4
		J Veselý	6	7	77															M Fucsovics	6	6	66	6
		Y Hanfmann	1	5	65						J Veselý	3	4r
		M Fucsovics	5	6	7	6					M Fucsovics	6	5
	19	J Sinner	7	3	5	3																							M Fucsovics	6	4	4	6	6
	26	F Fognini	77	6	6																							5	A Rublev	3	6	6	0	3
		A Ramos Viñolas	64	2	4					26	F Fognini	6	6	0	6
		P Cuevas	7	4	4	4					L Đere	3	4	6	4
		L Đere	5	6	6	6													26	F Fognini	3	7	4	2
		L Harris	6	6	78														5	A Rublev	6	5	6	6
		R Berankis	3	4	66						L Harris	1	2	5
		F Delbonis	6	4	1	2				5	A Rublev	6	6	7
	5	A Rublev	4	6	6	6

	First round									Second round									Third round									Fourth round
	3	S Tsitsipas	4	4	3
		F Tiafoe	6	6	6						F Tiafoe	6	6	6
		R Carballés Baena	3	3	3						V Pospisil	4	4	4
		V Pospisil	6	6	6															F Tiafoe	3	4	4
		E Gerasimov	6	3	77	6													25	K Khachanov	6	6	6
	WC	J Clarke	3	6	65	2					E Gerasimov	1	63	3
	Q	M McDonald	6	3	4	63				25	K Khachanov	6	77	6
	25	K Khachanov	3	6	6	77																						25	K Khachanov	3	6	6	5	10
	22	D Evans	77	6	7																								S Korda	6	4	3	7	8
		F López	64	2	5					22	D Evans	6	6	6
		D Lajović	6	7	3	4	6				D Lajović	3	3	4
		G Simon	4	5	6	6	3												22	D Evans	3	6	3	4
	Q	Z Zhang	6	65	77	3	2													S Korda	6	3	6	6
	Q	A Hoang	4	77	65	6	6			Q	A Hoang	5	4	4
		S Korda	6	6	65	77					S Korda	7	6	6
	15	A de Minaur	3	4	77	65

	First round									Second round									Third round									Fourth round
	10	D Shapovalov	6	4	6	5	6
	PR	P Kohlschreiber	4	6	3	7	4			10	D Shapovalov	w/o
		P-H Herbert	67	6	67	7	6				P Andújar
		P Andújar	79	4	79	5	8												10	D Shapovalov	6	6	6
	Q	O Otte	4	6	6	65	137												WC	A Murray	4	2	2
	Q	A Rinderknech	6	3	2	77	122			Q	O Otte	3	6	6	4	2
	WC	A Murray	6	6	5	6				WC	A Murray	6	4	4	6	6
	24	N Basilashvili	4	3	7	3																						10	D Shapovalov	6	6	7
	27	R Opelka	4	63	2																							8	R Bautista Agut	1	3	5
		D Koepfer	6	77	6						D Koepfer	6	68	77	5	6
		S-w Kwon	62	6	6	6					S-w Kwon	3	710	62	7	3
	Q	D Masur	77	3	4	4														D Koepfer	5	1	64
		F Bagnis	4	6	3	61													8	R Bautista Agut	7	6	77
		M Kecmanović	6	3	6	77					M Kecmanović	3	3	77	6	3
		J Millman	2	6	3	64				8	R Bautista Agut	6	6	63	3	6
	8	R Bautista Agut	6	3	6	77

	First round									Second round									Third round									Fourth round
	7	M Berrettini	6	3	6	6
		G Pella	4	6	4	0				7	M Berrettini	6	6	77
	LL	B van de Zandschulp	6	64	6	77				LL	B van de Zandschulp	3	4	64
	Q	G Barrère	2	77	1	63													7	M Berrettini	6	6	6
		C Moutet	4	4	0															A Bedene	4	4	4
		A Bedene	6	6	6						A Bedene	6	6	6
		Y Nishioka	77	2	6	63	6				Y Nishioka	1	0	2
	28	J Isner	65	6	3	77	4																					7	M Berrettini	6	6	6
	20	A Karatsev	64	66	3																								I Ivashka	4	3	1
		J Chardy	77	78	6						J Chardy	6	3	2	4
		J Munar	1	5	65						I Ivashka	4	6	6	6
		I Ivashka	6	7	77															I Ivashka	6	6	6
		K Nishikori	6	6	6															J Thompson	4	4	4
		A Popyrin	4	4	4						K Nishikori	5	4	7	3
		J Thompson	78	77	2	2	6				J Thompson	7	6	5	6
	12	C Ruud	66	63	6	6	2

	First round									Second round									Third round									Fourth round
	16	F Auger-Aliassime	6	6	6
		T Monteiro	3	3	3					16	F Auger-Aliassime	6	4	77	6
		J-W Tsonga	5	77	7	4	3				M Ymer	4	6	64	1
		M Ymer	7	64	5	6	6												16	F Auger-Aliassime	2	6	0
		JI Londero	63	0	6	3														N Kyrgios	6	1	0r
		G Mager	77	6	4	6					G Mager	67	4	4
		N Kyrgios	6	4	3	6	9				N Kyrgios	79	6	6
	21	U Humbert	4	6	6	1	7																					16	F Auger-Aliassime	6	78	3	3	6
	31	T Fritz	7	3	6	7																						4	A Zverev	4	66	6	6	4
	Q	B Nakashima	5	6	4	5				31	T Fritz	6	77	4	64	6
		S Johnson	79	6	7						S Johnson	4	64	6	77	4
		D Novak	67	2	5														31	T Fritz	77	4	3	64
		T Sandgren	6	65	6	6													4	A Zverev	63	6	6	77
		N Gombos	4	77	1	3					T Sandgren	5	2	3
	Q	T Griekspoor	3	4	1					4	A Zverev	7	6	6
	4	A Zverev	6	6	6

	First round									Second round									Third round									Fourth round
	6	R Federer	6	63	3	6	0
		A Mannarino	4	77	6	2	0r			6	R Federer	77	6	6
		R Gasquet	77	4	6	6					R Gasquet	61	1	4
		Y Sugita	64	6	2	1													6	R Federer	6	6	5	6
		F Krajinović	65	4	5														29	C Norrie	4	4	7	4
	WC	A Bolt	77	6	7					WC	A Bolt	3	1	2
		L Pouille	78	5	2	5				29	C Norrie	6	6	6
	29	C Norrie	66	7	6	7																						6	R Federer	7	6	6
	23	L Sonego	6	7	6																							23	L Sonego	5	4	2
		P Sousa	2	5	0					23	L Sonego	4	6	77	6
		DE Galán	6	4	7	7					DE Galán	6	3	63	1
		F Coria	4	6	5	5													23	L Sonego	6	6	6
		J Duckworth	6	6	6															J Duckworth	3	4	4
		R Albot	4	4	1						J Duckworth	7	64	6	6
		S Querrey	78	6	7						S Querrey	5	77	3	2
	11	P Carreño Busta	66	4	5

	First round									Second round									Third round									Fourth round
	14	H Hurkacz	6	77	6
		L Musetti	4	65	1					14	H Hurkacz	6	6	6
		E Ruusuvuori	4	6	2	6	4				M Giron	3	2	4
		M Giron	6	2	6	0	6												14	H Hurkacz	6	6	6
		M Kukushkin	4	2	1															A Bublik	3	4	2
		A Bublik	6	6	6						A Bublik	6	78	77
		F Verdasco	6	3	4	4				18	G Dimitrov	4	66	64
	18	G Dimitrov	3	6	6	6																						14	H Hurkacz	2	77	3	6	6
	32	M Čilić	77	77	6																							2	D Medvedev	6	62	6	3	3
		S Caruso	65	61	1					32	M Čilić	6	3	6	77
	Q	M Trungelliti	1	6	6	3	4			Q	B Bonzi	4	6	3	65
	Q	B Bonzi	6	1	4	6	6												32	M Čilić	77	6	3	3	2
	LL	Y Uchiyama	3	77	2	6	3												2	D Medvedev	63	3	6	6	6
	WC	C Alcaraz	6	64	6	3	6			WC	C Alcaraz	4	1	2
		J-L Struff	4	1	6	63				2	D Medvedev	6	6	6
	2	D Medvedev	6	6	4	77

The following are the seeded players. Seedings are based on ATP rankings as of 21 June 2021. Rankings and points are as before 28 June 2021. Players will count either their 2021 points or 50% of their 2019 points, whichever is greater.^[16]

Seed	Rank	Player	Points before	2019 Points defending	Points won	Points after	Status
1	1	Novak Djokovic	12,113	2,000	2,000	12,113	Champion, defeated Matteo Berrettini [7]
2	2	Daniil Medvedev	10,280	90	180	10,370	Fourth round lost to Hubert Hurkacz [14]
3	4	Stefanos Tsitsipas	7,980	10	10	8,150^	First round lost to Frances Tiafoe
4	6	Alexander Zverev	7,305	10	180	7,475	Fourth round lost to Félix Auger-Aliassime [16]
5	7	Andrey Rublev	6,120	45	180	6,255	Fourth round lost to Márton Fucsovics
6	8	Roger Federer	4,815	1,200	360	4,215	Quarterfinals lost to Hubert Hurkacz [14]
7	9	Matteo Berrettini	4,468	180	1,200	5,488	Runner-up, lost to Novak Djokovic [1]
8	10	Roberto Bautista Agut	3,125	720	180	2,765	Fourth round lost to Denis Shapovalov [10]
9	11	Diego Schwartzman	3,060	90	90	3,060	Third round lost to Márton Fucsovics
10	12	Denis Shapovalov	2,915	10	720	3,625	Semifinals lost to Novak Djokovic [1]
11	13	Pablo Carreño Busta	2,905	10	10	2,905	First round lost to Sam Querrey
12	14	Casper Ruud	2,690	10	10	2,690	First round lost to Jordan Thompson
13	17	Gaël Monfils	2,568	10	45	2,603	Second round lost to Pedro Martínez
14	18	Hubert Hurkacz	2,533	90	720	3,163	Semifinals lost to Matteo Berrettini [7]
15	15	Alex de Minaur	2,690	45	10	2,668	First round lost to Sebastian Korda
16	19	Félix Auger-Aliassime	2,468	90	360	2,738	Quarterfinals lost to Matteo Berrettini [7]
17	20	Cristian Garín	2,440	10	180	2,610	Fourth round lost to Novak Djokovic [1]
18	21	Grigor Dimitrov	2,431	10	45	2,466	Second round lost to Alexander Bublik
19	23	Jannik Sinner	2,320	(35)†	10	2,320^	First round lost to Márton Fucsovics
20	24	Aslan Karatsev	2,304	(15)†	10	2,304^	First round lost to Jérémy Chardy
21	25	Ugo Humbert	2,270	180	10	2,180	First round lost to Nick Kyrgios
22	26	Dan Evans	2,151	90	90	2,151	Third round lost to Sebastian Korda
23	27	Lorenzo Sonego	2,038	10	180	2,208	Fourth round lost to Roger Federer [6]
24	28	Nikoloz Basilashvili	1,985	45	10	1,975^	First round lost to Andy Murray [WC]
25	29	Karen Khachanov	1,965	90	360	2,235	Quarterfinals lost to Denis Shapovalov [10]
26	31	Fabio Fognini	1,868	90	90	1,868	Third round lost to Andrey Rublev [5]
27	32	Reilly Opelka	1,806	90	10	1,761	First round lost to Dominik Koepfer
28	33	John Isner	1,775	45	10	1,753	First round lost to Yoshihito Nishioka
29	34	Cameron Norrie	1,770	45	90	1,815	Third round lost to Roger Federer [6]
30	35	Alejandro Davidovich Fokina	1,723	(20)†	10	1,723^	First round lost to Denis Kudla [Q]
31	40	Taylor Fritz	1,590	45	90	1,635	Third round lost to Alexander Zverev [4]
32	37	Marin Čilić	1,660	45	90	1,705	Third round lost to Daniil Medvedev [2]

† The player did not qualify for the tournament in 2019. Accordingly, points defending from the ATP Challenger Tour are deducted instead.
^ Because the 2021 tournament was non-mandatory, the player substituted his 19th best result in place of the points won in this tournament.

The following players would have been seeded, but withdrew before the tournament began. Only half of their defending points are deducted.

Rank	Player	Points before	Points defending	Points after	Withdrawal reason
3	Rafael Nadal	8,630	720	8,270	Foot injury
5	Dominic Thiem	7,425	10	7,425^	Ongoing wrist injury
16	David Goffin	2,680	360	2,500	Ankle injury
22	Milos Raonic	2,428	180	2,338	Ongoing calf injury
30	Stan Wawrinka	1,944	45	1,922	Foot injury
36	Borna Ćorić	1,713	0	1,736^	Shoulder surgery

^ Because the 2021 tournament was non-mandatory, the player substituted his 19th best result in place of the points won in this tournament.

The following players were awarded wild cards into the main draw.^[17][18]

• 2021 Wimbledon Championships – Day-by-day summaries

• Men's singles draw
• The Championships 2021 – Gentlemen's Singles