Chemical compound
Pharmaceutical compound
JWH-184 is a synthetic cannabinoid receptor ligand from the naphthylmethylindole family. It is the carbonyl-reduced derivative of related compound JWH-122 . The binding affinity of JWH-184 for the CB1 receptor is reported as Ki = 23 ± 6 nM.[ 1]
In the United States, all CB1 receptor agonists of the 3-(1-naphthylmethane)indole class such as JWH-184 are Schedule I Controlled Substances .[ 2]
See also
References
^ Huffman JW, Mabon R, Wu MJ, Lu J, Hart R, Hurst DP, et al. (February 2003). "3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB(1) cannabinoid receptor". Bioorganic & Medicinal Chemistry . 11 (4): 539– 49. doi :10.1016/s0968-0896(02)00451-0 . PMID 12538019 . S2CID 29107765 . ^ 21 U.S.C. § 812 Schedules of controlled substances
Phytocannabinoids comparison )
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