Highway 48 is a provincial highway in the Canadian province of Saskatchewan. The highway runs from the Trans-Canada Highway at White City east to the Manitoba — Saskatchewan border. It is about 238 kilometres (148 mi) long.^[1] Highway 48 was originally numbered as Highway 16 until the mid-1970s.

Highway 48 was known as Highway 16 until 1976. It was renumbered 48 when the Yellowhead Highway was designated as Highway 16 throughout the province.

The original Highway 48 was located in south-western Saskatchewan, travelling from the Willow Creek Border Crossing to Highway 13 at Govenlock.^[2] The route was renumbered to Highway 348 in the 1960s^[3] before becoming part of Highway 21 in the 1970s.^[4]

Highway 48 begins at Highway 1 (the Trans-Canada Highway) about 10 kilometres (6.2 mi) east of Regina at White City. It travels in an easterly direction towards Manitoba where it becomes Provincial Road 257. Major highways it intersects include 35, 47, 9, and 8.

Beginning at a diamond interchange with Highway 1, Highway 48 travels south through White City. From the south side of White City, it turns south-east for about 10 kilometres (6.2 mi) before turning due east at the junction with Old 16 Road. From that junction, Old 16 Road heads west to Highway 33 (near Kinookimaw) while Highway 48 carries on eastward for a further 9 kilometres (5.6 mi) before resuming a south-easterly direction near Davin. Carrying on from Davin, Highway 48 provides access to the communities of Vibank,^[5] Odessa,^[6] Kendal, Montmartre,^[7] Candiac, and Glenavon.^[8] The junction with Highway 35 is between Vibank and Odessa. Highway 48 crosses the Chapleau Lakes,^[9] which is the source of Moose Mountain Creek, between Kendal and Montmartre.

East of Glenavon, Highway 48 intersects with Highway 47 before continuing south-east to Highway 9. Communities along that stretch include Peebles,^[10] Windthorst,^[11] Kipling,^[12] and Kennedy.^[13] East of Kennedy, Highway 48 turns south and begins a 13-kilometre (8.1 mi) concurrency with Highway 9. At the northern slopes of the Moose Mountain Upland, the concurrency ends with Highway 9 continuing south into Moose Mountain Provincial Park and Highway 48 turning east towards Wawota.^[14] From Wawota, the highway passes through Fairlight,^[15] Walpole, and Maryfield^[16] and intersects Highway 8 before ending at the Manitoba border. The road carries on into Manitoba as Provincial Road 257 where it crosses Pipestone Creek and provides access to Kola. PR 257 eventually meets up with the Trans-Canada Highway at Virden, Manitoba.^[17]

Form west to east:

Rural municipality	Location	km[1]	mi	Destinations	Notes
Edenwold No. 158	White City	0.0	0.0	Highway 1 (TCH) – Regina, Winnipeg	Interchange; Hwy 1 exit 217
	​	7.7	4.8	Highway 622 – Balgonie, Kronau
South Qu'Appelle No. 157	​	16.3	10.1	Highway 621 – Lajord
Lajord No. 128	Davin	22.3	13.9	Highway 620 north – McLean	West end of Hwy 620 concurrency
Francis No. 127	​	29.5	18.3	Highway 620 south – Sedley	East end of Hwy 620 concurrency
	Vibank	34.0	21.1		centre
	​	40.3	25.0	Highway 35 – Qu'Appelle, Francis, Weyburn
	Odessa	46.3	28.8		centre
Montmartre No. 126	Kendal	59.5	37.0	Highway 619 north – Indian Head
	Montmartre	71.7	44.6	Highway 606 north – Sintaluta	West end of Hwy 606 concurrency
		72.5	45.0	Highway 606 south – Fillmore	East end of Hwy 606 concurrency
	​	84.7	52.6	Highway 617 north – Wolseley	West of Candiac; west end of Hwy 617 concurrency
	Glenavon	94.3	58.6	Highway 617 south	East end of Hwy 617 concurrency
Chester No. 125	​	103.4	64.2	Highway 47 – Grenfell, Stoughton, Estevan
	Peebles	110.4	68.6	Highway 616 north – Grenfell	West end of Hwy 616 concurrency
	​	115.9	72.0	Highway 616 south	West of Windthorst; east end of Hwy 616 concurrency
Kingsley No. 124	Kipling	135.7	84.3	Highway 605 / Highway 709 east – Broadview
Hazelwood No. 94	No major junctions
Wawken No. 93	​	161.1	100.1	Highway 9 north – Whitewood, Yorkton	East of Kennedy; Hwy 48 branches south; west end of Hwy 9 concurrency
	​	171.1	106.3	Highway 711 west
	​	174.4	108.4	Highway 9 south – Moose Mountain Provincial Park, Carlyle	Hwy 48 branches east; east end of Hwy 9 concurrency
	Wawota	192.3	119.5	Highway 603 south
Walpole No. 92	​	201.7	125.3	Highway 601 north – Wapella	West end of Hwy 601 concurrency
	​	202.5	125.8	Highway 601 south	East end of Hwy 601 concurrency
Maryfield No. 91	Fairlight	219.0	136.1	Highway 8 – Moosomin, Redvers
	Maryfield	229.5	142.6	Highway 600 – Fleming
	​	237.8	147.8	PR 257 east – Virden	Continuation into Manitoba
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus       Route transition

• Transportation in Saskatchewan
• Roads in Saskatchewan