Two-time defending champions Bob Bryan and Mike Bryan defeated John Isner and Sam Querrey in the final, 6–7^(4–7), 6–2, [10–5] to win the doubles tennis title at the 2011 U.S. Men's Clay Court Championships.

	First round							Quarterfinals							Semifinals							Final
	1	B Bryan M Bryan	6	6
		J Cerretani A Shamasdin	0	2				1	B Bryan M Bryan	6	6
		S González R Mello	77	6					S González R Mello	3	4
		J Erlich R Schüttler	64	3											1	B Bryan M Bryan	7	6
	3	S Lipsky R Ram	3	3												P Cuevas G García-López	5	1
		P Cuevas G García-López	6	6					P Cuevas G García-López	3	6	[10]
	WC	R Harrison R Sweeting	1	1					T Rettenmaier H Zeballos	6	3	[4]
		T Rettenmaier H Zeballos	6	6																		1	B Bryan M Bryan	64	6	[10]
		B Becker I Kunitsyn	1	62																			J Isner S Querrey	77	2	[5]
		J Isner S Querrey	6	77					J Isner S Querrey	77	6
	WC	D Kudla D Young	6	6				WC	D Kudla D Young	65	1
	4	F Ferreiro A Sá	4	3												J Isner S Querrey	6	6
		C Berlocq T Gabashvili	7	6											2	E Butorac J-J Rojer	4	3
		J Murray M Zverev	5	0					C Berlocq T Gabashvili	65	4
		A Fisher S Huss	5	64				2	E Butorac J-J Rojer	77	6
	2	E Butorac J-J Rojer	7	77

• Main Draw