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Clocental (dolcental) is a carbamate-derived sedative hypnotic.[1][2]

Synthesis

Clocental was first prepared by the acylation of 1-ethynylcyclohexanol with allophanyl chloride.[3]

See also

References

  1. ^ Keil W, Muschaweck R, Rademacher E (August 1954). "[Sedative and hypnotic effect of the 1-ethinyl-cyclohexyl-allophante-(1)]". Arzneimittel-Forschung (in German). 4 (8): 477–479. PMID 13198744.
  2. ^ Preuss R, Kopp R (April 1959). "[Analysis of the renal excretion products of 1-ethinyl-cyclohexylacarbamate (valamine) & 1-ethinyl-cyclohexyl-allophanate (dolcental)]". Arzneimittel-Forschung (in German). 9 (4): 255–262. PMID 13651050.
  3. ^ US patent 2822379, Grimme W, Emde H, "Allophanates of alpha-ethynylcarbinols", issued 1958-02-04, assigned to Rheinpreussen AG fuer Bergbau und Chemie 

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