The 2022 Open delle Puglie was a professional tennis tournament played on outdoor clay courts. It was the first edition of the tournament and part of the 2022 WTA 125 tournaments, offering a total of $115,000 in prize money. It took place at the Circolo del Tennis at the Via Martinez in Bari, Italy between 5 and 11 September 2022.^[1][2]

Country	Player	Rank1	Seed
HUN	Panna Udvardy	78	1
MNE	Danka Kovinić	80	2
GER	Tatjana Maria	85	3
BEL	Maryna Zanevska	97	4
ITA	Elisabetta Cocciaretto	99	5
BRA	Laura Pigossi	100	6
FRA	Harmony Tan	112	7
SRB	Olga Danilović	114	8

• ¹ Rankings are as of 29 August 2022.

The following players received a wildcard into the singles main draw:

• Vittoria Paganetti
• Matilde Paoletti
• Lisa Pigato
• Lucrezia Stefanini

The following players received entry into the main draw through qualification:

• Nuria Brancaccio
• Paula Ormaechea
• Andreea Roșca
• Eva Vedder

The following players entered the main draw as lucky losers:

• Andrea Gámiz
• Ioana Loredana Roșca

Before the tournament

• Elina Avanesyan → replaced by Kateryna Baindl
• Ana Bogdan → replaced by Rebeka Masarova
• Lucia Bronzetti → replaced by Carolina Alves
• Clara Burel → replaced by Ioana Loredana Roșca
• Jule Niemeier → replaced by Andrea Gámiz
• Jasmine Paolini → replaced by Jaimee Fourlis
• Nuria Párrizas Díaz → replaced by Réka Luca Jani
• Mayar Sherif → replaced by Dalila Jakupović
• Viktoriya Tomova → replaced by Ylena In-Albon
• Zheng Qinwen → replaced by Raluca Șerban

Country	Player	Country	Player	Rank1	Seed
VEN	Andrea Gámiz	NED	Eva Vedder	240	1
POL	Paula Kania-Choduń	CZE	Renata Voráčová	242	2
	Angelina Gabueva	BRA	Laura Pigossi	252	3
BRA	Carolina Alves	ARG	María Lourdes Carlé	280	4

• ¹ rankings as of 29 August 2022.

The following pair received a wildcard into the doubles main draw:

• Vittoria Paganetti / Lucrezia Stefanini

• Julia Grabher def. Nuria Brancaccio 6–4, 6–2

• Elisabetta Cocciaretto / Olga Danilović def. Andrea Gámiz / Eva Vedder 6–2, 6–3