Defending champions Diede de Groot and Aniek van Koot defeated Yui Kamiji and Lucy Shuker in the final, 7–5, 3–6, [10–2] to win the women's doubles wheelchair tennis title at the 2022 Australian Open.
Seeds
Diede de Groot / Aniek van Koot (champions)
Yui Kamiji / 
Lucy Shuker (final)
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Bracket
| Semifinals | Final | ||||||||||||
| 1 | Diede de Groot Aniek van Koot
| 6 | 6 | ||||||||||
 Dana Mathewson Kgothatso Montjane
| 0 | 3 | |||||||||||
| 1 | Diede de Groot Aniek van Koot
| 7 | 3 | [10] | |||||||||
| 2 | Yui Kamiji Lucy Shuker
| 5 | 6 | [2] | |||||||||
Jiske Griffioen Zhu Zhenzhen
| 2 | 3 | |||||||||||
| 2 | Yui Kamiji Lucy Shuker
| 6 | 6 | ||||||||||
