The 3rd Syracuse Grand Prix was a non-championship Formula Two motor race held in Syracuse, Sicily on 22 March 1953. The race was won by Emmanuel de Graffenried in a Maserati A6GCM. Louis Chiron was second in an O.S.C.A. Tipo 20 and Rodney Nuckey third in a Cooper T23-Bristol. Alberto Ascari started from pole and set fastest lap but retired with mechanical failure, as did every other works Ferrari, in contrast to last year's 1-2-3 walkover.^[1][2]

Pos	No	Driver	Entrant	Car	Time/Retired	Grid
1	8	Emmanuel de Graffenried	Scuderia Enrico Platé	Maserati A6GCM	2:57:31, 148.10kph	4
2	4	Louis Chiron	Louis Chiron	O.S.C.A. Tipo 20	+3 laps	7
3	16	Rodney Nuckey	Rodney Nuckey	Cooper T23-Bristol	+6 laps	10
4	14	Eric Brandon	Cooper Car Company	Cooper T20-Bristol	+6 laps	9
5	6	Peter Whitehead	Peter Whitehead	Cooper T24-Alta	+6 laps	8
NC	30	Charles de Tornaco	Ecurie Francorchamps	Ferrari 500		14
NC	18	Giovanni de Riu	Scuderia Enrico Platé	Maserati 4CLT/48		12
NC	22	Mario Raffaeli	Scuderia Marzotto	Ferrari 166		13
Ret	2	Giuseppe Farina	Scuderia Ferrari	Ferrari 500	61 laps, mechanical	2
Ret	26	Mike Hawthorn Alberto Ascari	Scuderia Ferrari	Ferrari 500	57 laps, valves	5
Ret	24	Alberto Ascari	Scuderia Ferrari	Ferrari 500	37 laps, valves	1
Ret	28	Sergio Mantovani	Officine Alfieri Maserati	Maserati A6GCM	36 laps, accident	11
Ret	10	Tom Cole	Atlantic Stable	Cooper T23-Bristol	36 laps, accident	6
Ret	12	Luigi Villoresi	Scuderia Ferrari	Ferrari 500	3 laps, valves	3
DNA	20		Officine Alfieri Maserati	Maserati A6GCM	entry withdrawn	-