Events from the year 1522 in art.

• Antonio da Correggio completes the frescoes of the Vision of St. John on Patmos in the church of San Giovanni Evangelista (Parma).
• Benedikt Dreyer completes a Gothic altar called the "Antonius altar" for the Burg church in Lübeck.
• Titian completes the Averoldi Polyptych for the Santi Nazaro e Celso (Brescia).
• Bernard van Orley completes a triptych for the Brotherhood of the Holy Cross in a chapel of the Saint Walburga church in Veurne.

• Hans Baldung – The Stoning of Saint Stephen
• Hans Holbein – The Body of the Dead Christ in the Tomb
• Ludovico Mazzolino
  • Christ and the Woman Taken in Adultery
  • Madonna and Child with St. Joseph
• Ortolano Ferrarese – Mourning the Dead Christ (Galleria Borghese, Rome)
• Lucas van Leyden – Virgin and Child with the Magdalene and a Donor

• Antonio Campi, Italian painter (died 1587)
• Bernardino Campi, Italian Renaissance painter (died 1591)
• Dirck Volckertszoon Coornhert, Dutch writer, engraver, philosopher, translator, politician and theologian (died 1590)
• Federico Brandani, Italian sculptor and stuccoist who worked in an urbane Mannerist style as a court artist (died 1575)
• Jean Cousin the Younger, French painter, sculptor (died 1595)
• Pietro Marescalchi, Italian Renaissance painter (died 1589)
• Ludger Tom Ring the Younger, German painter and draughtsman (died 1584)^[1]

• Giovanni Antonio Amadeo, Italian early Renaissance sculptor, architect and engineer (born c. 1447)^[2]
• Paolo Moranda Cavazzola, Italian painter active mainly in his hometown of Verona (born 1486)
• Piero di Cosimo, Florentine painter (born 1462)
• Fiorenzo di Lorenzo, Italian painter of the Umbrian school (born 1440)
• (died 1522-1532): Colijn de Coter, early Netherlandish painter who produced mainly altarpieces (born 1440/1445)