Trifluoroacetate

Trifluoroacetate
Identifiers
CAS Number	14477-72-6;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:27110;
ChemSpider	76197;
Gmelin Reference	82342
PubChem CID	84468;
UNII	MH3TVL33EZ;
CompTox Dashboard (EPA)	DTXSID60162799 ;
	InChI InChI=1S/C2HF3O2/c3-2(4,5)1(6)7/h(H,6,7)/p-1 Key: DTQVDTLACAAQTR-UHFFFAOYSA-M;
	SMILES C(=O)(C(F)(F)F)[O-];
Properties
Chemical formula	C2F3O2−
Molar mass	113.016 g·mol−1
Conjugate acid	Trifluoroacetic acid
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

Trifluoroacetate (C F₃COO^-) is a polyatomic ion, the anion that is the conjugate base of trifluoroacetic acid (CF₃COOH).

Production

The salts containing the trifluoroacetate anion can be made by an acid–base reaction between trifluoroacetic acid and a base, such as sodium hydroxide (NaOH) to give sodium trifluoroacetate (CF₃COONa):

CF₃COOH + NaOH ⟶ CF₃COONa + H₂O

Trifluoroacetic acid is one of the shortest possible perfluoroalkyl substances (PFAS). It is suspected to be a persistent pollutant.^[1]^[2]

^ Jagani, Ravikumar; Chovatiya, Jasmin; Patel, Hiraj; Andra, Syam S. (11 July 2025). "Trifluoroacetic Acid: An Ultra-Short PFAS with Emerging Environmental and Public Health Concerns". ACS ES&T Water. 5 (7): 3533–3537. Bibcode:2025ACSEW...5.3533J. doi:10.1021/acsestwater.5c00599.
^ National Center for Biotechnology Information (2025). PubChem Compound Summary for CID 84468, Trifluoroacetate. Retrieved October 11, 2025 from https://pubchem.ncbi.nlm.nih.gov/compound/Trifluoroacetate.