Macaya may refer to:

• Macaya (military leader), Kongolese-born Haitian revolutionary military leader
• Macaya (surname)

• Pic Macaya, the second-highest mountain in Haiti
  • Pic Macaya National Park
• Macayá River, a river of Colombia
• Casa Macaya [es], a Modernist building located in Barcelona
• Edificio Macaya [es], a historic building built in San José, Costa Rica

• Copa Macaya, a football competition contested by clubs from Catalonia, which ran from 1900 until 1903
• Macaya breast-spot frog, a species of frog in the family Eleutherodactylidae

• Macaye, a commune in the Pyrénées-Atlantiques department in south-western France