TÄNA AJALOOS, 11. juuli ⟩ Avati Tallinna teletorn

DADLE ([D-Ala², D-Leu⁵]-Enkephalin) is a synthetic opioid peptide with analgesic properties. Although it is often considered a selective δ-opioid receptor agonist, it also binds to the μ₁ subtype of μ-opioid receptors.

Treatment with DADLE results in transient depression of mean arterial blood pressure and heart rate.^[1]^[2]

Its peptide sequence is Tyr-D-Ala-Gly-Phe-D-Leu.

References

↑ "Medical Dictionary Online". Archived from the original on 2007-08-28. Retrieved 2007-11-10.
↑ Online Medical Dictionary, enkephalin, leucine-2-alanine^{[link removed]}