First Newcastle ministry
Cabinet of Great Britain
1754 – 1756
Thomas Pelham-Holles, 1st Duke of Newcastle, was prime minister and led the government.
Date formed	16 March 1754 (1754-03-16)
Date dissolved	11 November 1756 (1756-11-11)
People and organisations
Monarch	George II
Prime Minister	Thomas Pelham-Holles, 1st Duke of Newcastle
Member party	Whigs
Status in legislature	Majority
Opposition party	Tories
Opposition leader	Sir Edmund Isham, 6th Baronet
History
Election	1754 general election
Legislature terms	1754–1761
Predecessor	Broad Bottom ministry
Successor	Pitt–Devonshire ministry

From 1754 to 1756, Thomas Pelham-Holles, 1st Duke of Newcastle headed the government of Great Britain. After the death of the previous prime minister, his brother Henry Pelham, Newcastle had formed a new administration of Whigs. He remained in power until 1756 when his government collapsed following the fall of Minorca and the fierce criticism that he had come under for his handling of the Seven Years' War that was engulfing Europe.

Among the most influential members of the first Newcastle ministry was Henry Fox, who served as Leader of the House of Commons from November 1755, having initially entered the Cabinet in his earlier position of Secretary at War in December 1754.

It is unclear who was a member of the Cabinet.

• 11th Parliament of Great Britain
• 1754 British general election
• Great Britain in the Seven Years' War