Kumamoto is a city in Japan.

Kumamoto may also refer to:

• Kumamoto Prefecture, a prefecture of Japan
• Kumamoto Domain, a historical region in Japan
• Kumamoto Station, a station in Kumamoto City
• Kumamoto Airport, an airport in Kumamoto Prefecture
• TV Kumamoto, a television station in Kumamoto Prefecture, Japan
• Kumamoto Kenmin Televisions, a television station in Kumamoto Prefecture, Japan
• RKK Kumamoto Broadcasting, a radio and television broadcaster in Kumamoto Prefecture, Japan
• Kumamoto Asahi Broadcasting, a television station in Kumamoto Prefecture, Japan
• Pedro Kumamoto (born 1990), Mexican politician
• Kumamoto oyster, a species of edible oyster