Fictional groups and organizations which specialize in investigating and researching paranormal phenomena, and/or to proactively combat and neutralize supernatural security threats to public safety, such as hostile predatory monsters or occultist criminal activity.

While these organizations are often portrayed as being government-affiliated (civilian/military/paramilitary/police) intelligence agencies (and/or as state-sponsored scientific research institutions), this category is also inclusive of large private non-governmental organizations, along with smaller informal groups of non-state actors as well.