3,4-Methylenedioxy-N-propylamphetamine

MDPR
Clinical data
Other names3,4-Methylenedioxy-N-propylamphetamine; MDPR; N-Propyl-MDA
Routes of
administration
Oral[1]
Drug classPsychoactive drug[1]
ATC code
  • None
Pharmacokinetic data
Duration of actionUnknown[1]
Identifiers
  • N-[1-(2H-1,3-benzodioxol-5-yl)propan-2-yl]propan-1-amine
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.217.125 Edit this at Wikidata
Chemical and physical data
FormulaC13H19NO2
Molar mass221.300 g·mol−1
3D model (JSmol)
  • CC(NCCC)Cc1ccc2OCOc2c1
  • InChI=1S/C13H19NO2/c1-3-6-14-10(2)7-11-4-5-12-13(8-11)16-9-15-12/h4-5,8,10,14H,3,6-7,9H2,1-2H3
  • Key:LBXMQBTXOLBCCA-UHFFFAOYSA-N
  (verify)

MDPR, also known as 3,4-methylenedioxy-N-propylamphetamine or as N-propyl-MDA, is a lesser-known psychoactive drug and a substituted amphetamine.[1][2]

Use and effects

In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists MDPR's minimum dose as 200 mg orally and its duration as unknown.[1][2] MDPR is described as a "promoter"; by itself it has almost no effects on the mind, but it promotes the effects of hallucinogens, similarly to the closely related MDPH.[1] Shulgin reported that 160 mg of MDPR strongly enhanced the effects of a small (60 μg) dose of LSD,[1] and that similar enhancement of hallucinogenic effect was noted when mixing MDPR with other drugs such as psilocybin, mescaline, 2C-B, and 2C-T-7.[1] The reason for this synergistic action of MDPR has not been elucidated.[1]

Chemistry

Synthesis

The chemical synthesis of MDPR has been described.[1]

See also

References

  1. ^ a b c d e f g h i j Shulgin, Alexander; Shulgin, Ann (September 1991). PiHKAL: A Chemical Love Story. Berkeley, California: Transform Press. ISBN 0-9630096-0-5. OCLC 25627628. MDPR entry
  2. ^ a b Shulgin AT (2003). "Basic Pharmacology and Effects". In Laing RR (ed.). Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. pp. 67–137. ISBN 978-0-12-433951-4. Archived from the original on 13 July 2025.